Researcher awarded $1.8 million grant to explore how chronic stress impacts cancer development – News-Medical.net

February 3, 2017
 By Alyssa
February 3, 2017
 By Alyssa

Researcher awarded $1.8 million grant to explore how chronic stress impacts cancer development – News-Medical.net

A 1.8 million dollar grant, from the National Cancer Institute, has been awarded to Wenwei Wu, PhD, of Rutgers Cancer Institute of New Jersey for research into the p53 protein. The p53 protein has been shown to prevent cancer, and the loss of the protein leads to tumor growth and development.

Key Takeaways:

  • The aim is to explore how chronic stress impacts cancer development, especially when cancers containing a mutation in p53, and identify molecular targets that would disrupt the effect of chronic stress on cancer development.
  • The p53 protein plays a central role in preventing cancer development, as loss of its tumor suppressor function has been shown to contribute greatly to cancer development.
  • In identifying molecular targets that impact stress signaling, there is an opportunity to develop novel therapies to treat those with mutated p53 cancers.

“The p53 protein plays a central role in preventing cancer development, as loss of its tumor suppressor function has been shown to contribute greatly to cancer development.”

http://www.news-medical.net/news/20170119/Researcher-awarded-2418-million-grant-to-explore-how-chronic-stress-impacts-cancer-development.aspx

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