Now, researchers from the University of Missouri School of Medicine suggest that the gastrointestinal issues in these individuals with autism may be related to an increased reaction to stress. We know that it is common for individuals with autism to have a more intense reaction to stress, and some of these patients seem to experience frequent constipation, abdominal pain or other gastrointestinal issues, said David Beversdorf, M.D., associate professor in the departments of radiology, neurology and psychological sciences at MU and the MU Thompson Center for Autism and Neurodevelopmental Disorders.